In this letter, we report the development of a new BiTE (Nb-BiTE) platform that was exemplified with two Nbs, specific to the CD3 of T-cells and a TAA (e.g., CD105) for enhanced solid tumor treatment ...
CD3e molecule, epsilon (CD3E), is a single-pass type I membrane glycoprotein found on T cells. It contains one Ig-like (immunoglobulin-like) domain and one ITAM domain. CD3E, along with CD3-gamma, CD3 ...
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