This program is used to display, modify, and compare the codons of gene. It shows the codons and GC content of the gene in the form of visual graphics, and the user can modify the codons to optimize ...

Previously, Tuller et al. found that the first 30–50 codons of the genes of yeast and other eukaryotes are slightly enriched for rare codons. They argued that this slowed translation, and was adaptive ...

The main focus of this study is, to understand provision of reducing impact of frame shift mutations in genetic code table, which may occur when protein translation starts not at the first nucleotide ...

A. Usage of each codon per 1000 codons and the Ribosome Residence Time (RRT) at position 6 (the A-site of the ribosome). The p-value for a difference between the calculated RRT value and an RRT value ...

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Despite the highly conserved nature of the genetic code, the frequency of usage of each codon can vary significantly. The evolution of codon usage is shaped by two main evolutionary forces: mutational ...

We present an evolutionary hypothesis assuming that signals marking nucleotide synthesis (DNA replication and RNA transcription) evolved from multi- to unidimensional structures, and were carried over ...