Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. There are increasing evidences to suggest the complement system may play a significant role on the ...

In hemodialysis (HD), complement activation, bioincompatibility, and inflammation are intricately intertwined. In the 1970s, as HD became a routine therapy, the observation of complement pathway ...

The domain of cancer treatment has persistently been confronted with significant challenges, including those associated with recurrence and drug resistance. The complement system, which serves as the ...

The following is a summary of “Prognostic role of activation of the complement pathways in the progression of advanced IgA nephropathy to end-stage renal disease,” published in the October 2024 issue ...

Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway. Most of the proteins and glycoproteins that ...

Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway. Most of the proteins and glycoproteins that ...

Global understanding of complement has shifted and developed since the 21st century: from our idea of a blood-based antibiotic system to a global regulator of immunity and tissue homeostasis. Recent ...

Among individuals with paroxysmal nocturnal hemoglobinuria (PNH), use of a triple-fusion (TriFu) protein approach has been shown to produce a potent complement inhibitor that effectively can block all ...

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