Somatic copy number aberrations (SCNAs) are a hallmark of cancer, involving large-scale genomic alterations that drive tumorigenesis and cancer progression by affecting gene dosage and altering the ...
A key driver of cancer development and progression is genomic instability. This includes mutational processes and chromosomal instability (CIN), resulting in SNVs and SCNAs, respectively. Multiple ...
Neoadjuvant pamiparib in patients with newly diagnosed advanced ovarian cancer: A single-arm, prospective phase II trial. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...
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