Relapse to drug abuse is often caused by exposure to drug-associated cues that evoke craving. Therefore, disruption of the cue–drug memory can prevent relapse. Memories destabilize and become ...

Version of Record: This is the final version of the article. The authors attempted to replicate previous work showing that counterconditioning leads to more persistent reduction of threat responses, ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

It is unclear whether other types of disgust stimuli could have led to different results. Second, it is possible that a closer fit of CS and UCS could lead to stronger effects of the ...

For clinical purposes, the relevance of counterconditioning is to change maladaptive associations between cues associated with outcomes of a particular value so that, for example, feared objects or ...

Nocebo effects can adversely affect the experience of physical symptoms, such as pain and itch. Nocebo effects on itch and pain have shown to be induced by conditioning with thermal heat stimuli and ...

For example, imagine if every time your dog saw a person walk by the house, they lunged at the window, growled, barked, and scratched up your windowsill. These negative feelings and unwanted behaviors ...