Kabuki syndrome (KS) is a congenital malformation syndrome caused by mutations in the KMT2D and KDM6A genes that encode histone modification enzymes. Although KS is considered a single gene disorder, ...

Large-scale de novo nucleic acid synthesis is a powerful tool enabling researchers to better understand and engineer biological systems. Fields ranging from genomics to nucleic acid therapeutics to ...

Amplified RNA (aRNA) synthesized by T7 linear amplification is frequently used for gene expression analysis on microarrays. Single stranded DNA (ssDNA) is however mostly used as target in microarray ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

Processes Involved in Using DNA Microarray Instrumentation in Protein Microarray Workflow Protein microarrays offer the ability to measure protein expression and antibody binding in a high-throughput ...