Most if not all organs in mammals have adult stem cells that have some capacity to make and repair tissues throughout the lifetime of the organism. To understand how stem cells achieve these functions ...

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease of the nasal mucosa, and epithelial–mesenchymal transition (EMT) is thought to be an essential process in the ...

A distinct signaling pathway called TNF- drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF- program and become invasive ...