Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...

Immunotherapy is increasingly becoming standard therapy in cancer, with technology, such as checkpoint inhibitors and cell therapy, raising the efficacy bar in many forms of the disease. But the ...

The complement system is a well-characterized key regulator of both innate and adaptive immunity 1,2 with over 50 known complement-related genes in rodents, consisting of complement cascade components ...

The complement system is a crucial part of the immune system. Its activation triggers the formation of the membrane attack complex, which eliminates pathogens and damaged cells 1. The complement ...