For the majority of common human diseases, only a small fraction of the heritability can be attributed to known genetic variation. A widely held hypothesis is that the remaining heritability can be ...

Any organism is a by-product of both its genetic makeup and the environment. To understand this in detail, we must first appreciate some basic genetic vocabulary and concepts. Here, we provide ...

As whole human genome and targeted sequencing start to offer the real potential to inform clinical decisions 1,2,3,4, it is becoming critical to assess the accuracy ...