Human cellular reprogramming to induced pluripotency is still an inefficient process, which has hindered studying the role of critical intermediate stages. Here we take advantage of high efficiency ...

Direct neuronal reprogramming offers a promising strategy to generate functional neurons from somatic cells without passing through a pluripotent state. However, the cellular heterogeneity and ...

Cellular reprogramming is the hottest topic in longevity science, with tech titans like Sam Altman investing in it. It's now ...

World’s first anti-ageing gene therapy trial begins as ER-100 is injected into a human eye, testing partial cellular ...

Researchers from Monash University in Melbourne and The University of Western Australia have demonstrated how a reprogramming method imitates embryonic epigenetic reset. Transient naive treatment (TNT ...

For decades, the idea of resetting the biological clock sounded more like speculative fiction than clinical strategy. The discovery of Yamanaka factors by Nobel laureate Shinya Yamanaka, which can ...

Zhou’s study, "TBX20 improves contractility and mitochondrial function during direct human cardiac reprogramming," was recently published in Circulation. The most common cause of death worldwide is ...