Primary lymphoid organs, such as the thymus, provide the specialized microenvironments that are required for the development of lymphoid cells. In addition, they support the necessary quality-control ...

Age-related regression of the thymus is associated with a decline in naïve T cell output. This is thought to contribute to the reduction in T cell diversity seen in older individuals and linked with ...

Thymus Research and Development: A New Look to the Past, Current Knowledge, and Future Perspectives ...