Mannan-binding lectin (MBL) and ficolins distinguish between self, non-self and altered-self by recognizing patterns of ligands on the surface of microorganisms or aberrant cells. When this happens ...

MBL (mannose-binding lectin), a pattern recognition molecule circulating in complex with MASPs (MBL-associated serine proteases), activates the lectin complement pathway and facilitates thrombin ...

Therefore, we became interested in the potential role of the MBL pathway of ComC activation in triggering the mobilization of HSPCs after administration of G-CSF or AMD3100. MBL is a soluble ...

The lectin pathway is the third pathway in the complement cascade, discovered after the classical and alternative pathways. It more closely resembles the classical pathway due to similar binding ...

WOODS HOLE, Mass.-- The front line of the human immune system is made up of T-cells: white blood cells that circulate in the body and scan for foreign invaders and infections. If a T-cell surface ...