Schizophrenia is a common psychiatric disorder involving approximately 1% of the population worldwide. Family, twin, and adoption studies suggest genetic factors contribute to this illness (Lang et al ...

Next-generation sequencing platforms have amplified the information content of genetic variation studies by a massive reduction of cost and sequencing effort 1,2,3,4. However, the full potential of ...

Tecan has announced the launch of HS 400 Pro™ and HS 4800 Pro™ automated microarray stations. These arrays are based on the HS series of hybridization stations and have been designed to maximize the ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

Metronomic oral cyclophosphamide (CPM) and prednisolone in elderly patients (pts) with inoperable or metastatic soft tissue sarcoma (STS). No significant financial relationships to disclose. This is ...

The "capture" can be realized through the hybridization of fragmented DNA with baits complementary to regions of interest, either on a microarray chip or free in solution. In-solution hybridization ...

To prevent outbreaks of water- or food-borne illnesses, scientists need rapid, sensitive methods to detect pathogenic bacteria such as Escherichia coli, Salmonella enterica, and Campylobacter jejuni.

The expression pattern of a single gene or multiple genes can be investigated using a technique RNA microarray. In this technique, RNA molecules are ‘spotted’ onto a solid surface. These act as probes ...