When AlphaFold solved the protein-folding problem in 2020, it showed that artificial intelligence could crack one of biology’s deepest mysteries: how a string of amino acids folds itself into a ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

ENCODE has identified 400 regions of ‘junk’ or non-coding DNA that may have a bearing on disease states, and the implications for pharma and patients are huge The announcement in September that hefty ...

多くの配列バリアントがヒトの複雑な形質や疾患と関連付けられてきたが、それらの大半はノンコーディングDNA上にあるために、その生物学的機能の解明はいまだに困難である。今回我々は、SNP-SELEX（single-nucleotide polymorphism evaluation by systematic evolution of ligands ...

Researchers at Pohang University of Science and Technology (POSTECH) have built a platform that steers cell behavior using ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

While it was once believed that genes regulated biological functions almost exclusively by being transcribed to coding RNAs that were then translated into proteins, it is now known that the picture is ...