The syndrome of normal pressure hydrocephalus (NPH) was first described by Adams et al. almost 60 years ago, in patients with a classical clinical triad of ataxia, incontinence and dementia 1. These ...

The central nervous system (CNS) lacks lymphatic vessels, making the drainage of interstitial fluid (ISF) within the CNS distinct from that in other organs. The cerebrospinal fluid (CSF) enveloping ...

The typical signs and symptoms of idiopathic NPH are shown. In a retrospective study involving 418 patients with shunt-responsive idiopathic NPH, 96% of the patients had gait difficulty, 76% had ...

Biomedical engineers at Duke University have developed a technique to noninvasively visualize the brain's waste-removal system in unprecedented detail. This new imaging approach allows researchers to ...

Cerebrospinal fluid (CSF) and other biomarkers differ for individuals with Alzheimer disease and cognitively normal controls, with the estimated times of divergence varying from 18 to six years before ...

Scientists at the Institute for Basic Science (IBS) have uncovered a non-invasive method to boost the brain’s natural waste drainage system—a discovery that they suggest could open new avenues for ...

New neuroimaging research shows that when sleep-deprived people lose focus, the brain briefly shifts toward sleep-like physiology, offering fresh insight into why cognitive performance declines ...

Massage might help your brain flow regain its mojo. On June 4 in Nature, researchers led by Gou Young Koh at the Institute for Basic Science in Daejeon, South Korea, mapped the labyrinth of lymphatics ...