With the success of structural biology and the advancements in deep-learning-based structure predictions, rapid and accurate structural comparisons among macromolecular structures have become ...

AlphaFold is making great progress in protein structure prediction, not only for single-chain proteins but also for multi-chain protein complexes. When using AlphaFold-Multimer to predict ...

University of Missouri researchers have released the world's largest collection of protein models with quality assessment—a groundbreaking new resource that could accelerate drug development for ...

Update (July 29, 2022): Nature reports that AlphaFold has now predicted the structure of more than 200 million proteins spanning 1 million species—nearly every known protein. These structures will ...

In biology, proteins don’t go it alone. They fold up in complexes and interact with each other to get stuff done. Those interactions create challenges for scientists working to predict protein ...

Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have ...

Using artificial intelligence and deep learning, researchers have developed a neural network that 'hallucinates' the structures of new protein molecules. The scientists made up completely random ...

A South Korean research team has successfully designed large protein structures that replicate the natural assembly principles of viruses in nature by collaborating with a Nobel laureate and utilizing ...

The three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary relationships in the tree of life, according to a study in Nature Communications . It is the first time ...

Scientists from Scripps Research have uncovered new structures of transthyretin, a protein that moves important hormones like thyroxine through blood and spinal fluid. Misfolded versions of the ...