Europe PMC

A two-sample Mendelian randomization study of mutual relations of six types of diets in atopic dermatitis.

In the continuous endeavor to find safe and efficient treatments for Atopic Dermatitis (AD), there remains a considerable focus on dietary adjustments. Nevertheless, the limited availability of ...
Frontiers

Verification of the Role of ADAMTS13 in the Cardiovascular Disease Using Two-Sample Mendelian Randomization

1 Department of Cardiology, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China 2 Department of Cardiology, China-Japan Friendship Hospital, Beijing, China Objective: ...
Frontiers

Using a Two-Sample Mendelian Randomization Method in Assessing the Causal Relationships Between Human Blood Metabolites and Heart Failure

Background: Heart failure (HF) is the main cause of morbidity and mortality worldwide, and metabolic dysfunction is an important factor related to HF pathogenesis and development. However, the causal ...
Europe PMC

Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome.

The sample size required for a given power of Mendelian randomization investigation depends greatly on the proportion of variance in the risk factor explained by the instrumental variable. The ...
University of Vermont

Randomization Test on Means of Matched Pairs

In some ways the randomization test on the means of two matched samples is even simpler than the corresponding test on independent samples. From the parametric t test on matched samples, you should ...