Hepatitis B virus (HBV) whole genome sequencing (WGS) is currently limited as the DNA viral loads (VL) of many clinical samples are below the threshold required to generate full genomes using current ...

Single-cell sequencing methods are revolutionizing our ability to characterize tissues across developmental stages, diseases and individuals, and following large-scale genetic perturbations 1,2.

In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...

Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers' ability to detect complex genetic alterations in cancer genomes.

Next-generation sequencing (NGS) has revolutionized genomics research, enabling scientists to sequence millions of DNA fragments simultaneously with unprecedented speed and efficiency. However, many ...

An improved method for analyzing the expression of genes by single cells promises to enhance regenerative medicine therapy as well as disease research ...

While non-invasive prenatal testing (NIPT) has revolutionised prenatal diagnostics by allowing the detection of a number of genetic problems in a fetus, it is currently limited and thus misses many ...

The idea for the LRGASP Consortium was originally discussed among scientists at a conference in 2019.

Our food and our bodies are full of tiny protein fragments called peptides. These small chains of amino acids act as biological messengers, influencing processes ranging from sensory perception to ...

Technique that examines fragments of foetal DNA in mother’s bloodstream could limit need for invasive screening, according to researchers ...