A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

Researchers reveal the intricate molecular landscape of triple-negative breast cancer (TNBC), uncovering actionable spatial archetypes and gene signatures that pave the way for personalized therapies ...

The field of spatial transcriptomics utilizes technologies that map gene expression data to specific cellular locations within tissues. While traditional RNA sequencing methods generate quantitative ...

A collaborative project has created a comprehensive guide to help standardize spatial transcriptomics practices. Spatial transcriptomics provides a unique perspective on the genes that cells express ...

Inflammatory bowel disease (IBD) is an umbrella term for Crohn's disease and ulcerative colitis, which both involve chronic inflammation ... | Cell And Molecular Biology ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...