Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

Will Kenton is an expert on the economy and investing laws and regulations. He previously held senior editorial roles at Investopedia and Kapitall Wire and holds a MA in Economics from The New School ...

Objectives We estimated the extent of the disparity between statistical significance and clinical importance in published randomised controlled trials (RCTs), and explored factors associated with this ...

The scientific world is abuzz following recommendations by two of the most prestigious scholarly journals – The American Statistician and Nature – that the term “statistical significance” be retired.

This week, The American Statistician published a special issue, "Statistical Inference in the 21st Century: A World Beyond p < 0.05," which includes 43 new papers by leading statisticians. The ...